What Cheers was to its (fictional) Boston neighborhood is what Twenty Manning Grill is to Rittenhouse Square. In other words, it’s the place everyone in the city’s toniest district seems to end up, no matter if they’re headed to the Orchestra or coming home from the gym, craving ceviche or jonesing for a half-baked chocolate chip cookie sundae. Restaurateur Audrey Taichman (of the adorable, across-the-street BYOB Audrey Claire, and boutique culinary-school sensation Cook) is responsible for both the casual-chic ambiance and carefully curated menu of international comfort foods. Under her command, the kitchen gives the same attention to the malted fries and impossibly airy tempura-battered sole (TMG’s fish and chips) as it does to a cloud-like wisp of lavender honey and ricotta beneath a quartet of gold and red beet wedges. Bulging burgers -- including bison, tuna and grass-fed beef --  arrive on rustic planks; mussels come by the aromatic bucketful. By contrast, a trio of mushroom ravioli and toothsome pork potstickers could double as modern art installations.